An aristocratic woman in 18th century England is expected to act in certain ways. But Mary has never let society's expectations stifle her: she writes celebrated poetry and articles advocating for equality, as well as endless, often scandalous, letters to her many powerful friends. However, Mary wants more from the world. Using her charm and connections, she engineers a job offer for her husband as ambassador to the Ottoman Empire. Travelling to Constantinople, Mary finally discovers the autonomous life she dreams of. And when she observes Turkish women 'engrafting' children against smallpox, she resolves to bring the miracle cure back to England. Despite this, Mary's reputation becomes increasingly tainted. Her inability to abide by the rules, her outspoken opinions on women's rights, and her search for love and desire at all costs gains her powerful enemies.